Direct Flights from Des Moines to Mesa
Mesa · Arizona
Nonstop service from DSM to AZA on Allegiant. Here's the schedule at a glance — plus what to do once you land.
How rare is this nonstop?
42 cities have a nonstop to Mesa, Des Moines among them.
How long to go to Mesa for, from Des Moines
2h 45m in the air, 1,136 miles. That is a long weekend without much friction, though three nights beats two once you add the airport time at both ends.
About Mesa

Mesa, population 518,000 (2019), is in Maricopa County. It is Arizona's third-largest city, and is part of the Greater Phoenix urban complex.
Summary from Wikivoyage (CC BY-SA).
Top things to do in Mesa
- Taliesin West is a studio and home developed by the American architect Frank Lloyd Wright in Scottsdale, Arizona, United States.
- The Arizona State Capitol is the seat of government for the U.S. state of Arizona and is located in its capital city of Phoenix.
- The Phoenix Zoo opened in 1962 and is the largest privately owned nonprofit zoo in the United States.
- The Heard Museum is a private, not-for-profit museum in Phoenix, Arizona, United States, dedicated to the advancement of American Indian art.
- The Phoenix Art Museum is the largest museum for visual art in the southwest United States. Located in Phoenix, Arizona, the museum is 285,000 square feet (26,500 m2).
- The Hohokam Pima National Monument is an ancient Hohokam village within the Gila River Indian Community, near present-day Sacaton, Arizona.
- Desert Botanical Garden is a 140-acre (57 ha) botanical garden located in Papago Park, at 1201 N. Galvin Parkway in Phoenix, central Arizona.
- The Cathedral of Saints Simon and Jude is the cathedral of the Roman Catholic Diocese of Phoenix in Phoenix, Arizona, in the United States. As of 2025, the rector of the cathedral is Monsignor Matthew Henry.
- The Buseck Center for Meteorite Studies was founded in 1960, on the Tempe Campus of Arizona State University, and houses the world's largest university-based meteorite collection.
- The Arizona State University Art Museum is an art museum operated by Arizona State University, located on its main campus in Tempe, Arizona.
- The St. Stephen Cathedral is a Ruthenian Greek Catholic cathedral located in Phoenix, Arizona, United States. It is the cathedral for the Holy Protection of Mary Byzantine Catholic Eparchy of Phoenix.
- Mystery Castle is located in the city of Phoenix, Arizona, in the foothills of South Mountain Park. It was built in the 1930s by Boyce Luther Gulley for his daughter Mary Lou Gulley.
Attraction descriptions from Wikipedia (CC BY-SA); place data from Wikidata (CC0).
Mesa weather, compared with Des Moines
24° warmer than Des Moines on average across the year, on daytime highs:
- January
- Mesa 65°F · Des Moines 31°F · 34° warmer
- April
- Mesa 84°F · Des Moines 62°F · 21° warmer
- July
- Mesa 104°F · Des Moines 86°F · 18° warmer
- October
- Mesa 88°F · Des Moines 64°F · 24° warmer
July averages 104°F, hot enough to plan the middle of the day around. Mesa is the steadier of the two, moving 39° between its coldest and warmest months where Des Moines moves 55°.
Daily highs averaged from Meteostat station records (CC BY 4.0), measured at each city's airport.
Planning a trip to Mesa
- Best time to visit
- The best time to visit Mesa is November–March, when daytime highs are a comfortable 65–75°F.
- How long to stay
- Mesa rewards a longer visit — a full week lets you explore its many sights, from Taliesin West, Arizona State Capitol, and Phoenix Zoo and beyond.
Frequently asked questions
- Is there a direct flight from Des Moines to Mesa?
- Yes — you can fly nonstop from Des Moines (DSM) to Mesa (AZA) on Allegiant.
- Which airlines fly nonstop from Des Moines to Mesa?
- Allegiant flies nonstop between Des Moines (DSM) and Mesa (AZA).
- How many nonstop flights are there from Des Moines to Mesa?
- There is about 1 nonstop departure per day (roughly 7 per week) from Des Moines to Mesa.
- How far is Mesa from Des Moines?
- Mesa is about 1,136 miles from Des Moines by air.
- What is there to do in Mesa?
- Popular things to do include Taliesin West, Arizona State Capitol, Phoenix Zoo, Heard Museum, and more.
More nonstop destinations from Des Moines near Mesa
Airports near Des Moines
The closest other departure airports to Des Moines — each opens up more nonstop destinations.